BDBM15250 7-chloro-3-oxo-11,18-dioxa-2,4,21,23-tetraazatricyclo[17.3.1.0^{5,10}]tricosa-1(22),5(10),6,8,19(23),20-hexaene-20-carbonitrile::CHEMBL374417::macrocyclic inhibitor 5d

SMILES: Clc1ccc2OCCCCCCOc3nc(NC(=O)Nc2c1)cnc3C#N

InChI Key: InChIKey=YORQHSLTMRRBGJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Human)	BDBM15250 (7-chloro-3-oxo-11,18-dioxa-2,4,21,23-tetraazatricy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM15250 (7-chloro-3-oxo-11,18-dioxa-2,4,21,23-tetraazatricy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair