BDBM152723 N-[3-({[(3S,5R)-5-({[3-(thiophene-2-imidamido)phenyl]methoxy}methyl)pyrrolidin-3-yl]oxy}methyl)phenyl]-2H-1λ⁴-thiophene-2-carboximidamide (28)

SMILES N=C(Nc1cccc(COC[C@H]2C[C@@H](CN2)OCc2cccc(NC(=N)c3cccs3)c2)c1)c1cccs1

InChI Key InChIKey=GPVRORSBZUBDJB-RPBOFIJWSA-N

Data  3 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 152723   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM152723(N-[3-({[(3S,5R)-5-({[3-(thiophene-2-imidamido)phen...)
Affinity DataKi:  21nMAssay Description:Inhibition of rat nNOS using L-arginine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM152723(N-[3-({[(3S,5R)-5-({[3-(thiophene-2-imidamido)phen...)
Affinity DataKi:  1.23E+3nMAssay Description:Inhibition of mouse macrophage iNOS using L-arginine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM152723(N-[3-({[(3S,5R)-5-({[3-(thiophene-2-imidamido)phen...)
Affinity DataKi:  3.17E+3nMAssay Description:Inhibition of bovine eNOS using L-arginine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase oxygenase(Bacillus subtilis (Firmicutes))
University Of California Irvine

LigandPNGBDBM152723(N-[3-({[(3S,5R)-5-({[3-(thiophene-2-imidamido)phen...)
Affinity DataKd:  7.73E+3nMAssay Description:In short, the difference between the imidazole-bound low-spin peak at 430 nm and the inhibitorbound high-spin peak at 395 nm was measured as a functi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed