BDBM155381 US9006282, Example 2, Compound 9::US9102656, Example 2, Compound 9

SMILES COc1ccc(OC2C[C@H](O)C[C@H](O2)\C=C\c2c(nc(nc2-c2ccc(F)cc2)N(C)S(C)(=O)=O)C(C)C)c(OC)c1

InChI Key InChIKey=CQYSSVVEFOVLEM-PCMIMOEYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 155381   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Redx Pharma

US Patent
LigandPNGBDBM155381(US9006282, Example 2, Compound 9 | US9102656, Exam...)
Affinity DataIC50:  2nMAssay Description:The following procedure was followed using a HMG-CoA Reductase assay kit obtained from Sigma-Aldrich (catalogue number CS1090). The assay is based on...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Redx Pharma

US Patent
LigandPNGBDBM155381(US9006282, Example 2, Compound 9 | US9102656, Exam...)
Affinity DataIC50:  2nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
In DepthDetails US Patent