BDBM16680 Mixture of trans methyl(cyclopropylmethyl)diastereomers.::N-[(2S,3S)-3-amino-1-(thiophen-3-yl)heptan-2-yl]-2-({[(1S,2S)-2-methylcyclopropyl]methyl}amino)-6-(N-methylmethanesulfonamido)pyridine-4-carboxamide::isonicotinamide, 19

SMILES CCCC[C@H](N)[C@H](Cc1ccsc1)NC(=O)c1cc(NC[C@H]2C[C@@H]2C)nc(c1)N(C)S(C)(=O)=O

InChI Key InChIKey=MSSOOXCWRUWADA-CZGNIMDHSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16680   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16680(Mixture of trans methyl(cyclopropylmethyl)diastere...)
Affinity DataIC50:  11nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair