BDBM18047 5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE::5-[(4-tert-butylphenyl)sulfanyl]quinazoline-2,4-diamine::GW995

SMILES CC(C)(C)c1ccc(Sc2cccc3nc(N)nc(N)c23)cc1

InChI Key InChIKey=MNYDVPDMLAJJPB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18047   

TargetDihydrofolate reductase(Homo sapiens (Human))
Gsk

LigandPNGBDBM18047(5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDI...)
Affinity DataIC50:  2.00E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Candida albicans)
Gsk

LigandPNGBDBM18047(5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDI...)
Affinity DataIC50:  8nMpH: 6.4 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair