BDBM18335 (2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-N-[(2S)-2-methyl-2-(methylcarbamoyl)ethyl]-2-(propan-2-yl)nonanamide::2,7-dialkyl-substituted 8-phenyl-octanecarboxamide, 44

SMILES CNC(=O)[C@@H](C)CNC(=O)[C@@H](C[C@H](O)[C@@H](N)C[C@H](Cc1ccc(OC)c(OCCCOC)c1)C(C)C)C(C)C

InChI Key InChIKey=BFIDKKSZGRMHCA-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18335   

TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18335((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed