BDBM190654 PT173

SMILES CCCCCCc1ccn(Cc2cccc(N)c2C)c(=O)c1

InChI Key InChIKey=PJADLCYVDLAZCT-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 190654   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
University Of Wuerzburg

LigandPNGBDBM190654(PT173)
Affinity DataKi:  2nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
University Of Wuerzburg

LigandPNGBDBM190654(PT173)
Affinity DataKi:  203nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190654(PT173)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University Of Wurzburg

LigandPNGBDBM190654(PT173)
Affinity DataIC50:  1.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair