BDBM19640 (3R)-3-(cyclohexylmethyl)-N-{2-[(4-fluorophenyl)amino]ethyl}-4-(morpholin-4-yl)-4-oxobutanamide::succinamide peptidomimetic, 6

SMILES Fc1ccc(NCCNC(=O)C[C@@H](CC2CCCCC2)C(=O)N2CCOCC2)cc1

InChI Key InChIKey=GBWWFYPYZLWCDD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19640   

TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19640((3R)-3-(cyclohexylmethyl)-N-{2-[(4-fluorophenyl)am...)
Affinity DataKi:  1.72E+3nM ΔG°:  -8.17kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19640((3R)-3-(cyclohexylmethyl)-N-{2-[(4-fluorophenyl)am...)
Affinity DataKi: >1.00E+5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19640((3R)-3-(cyclohexylmethyl)-N-{2-[(4-fluorophenyl)am...)
Affinity DataKi: >1.00E+5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed