BDBM19964 6-(4-hydroxyphenyl)-5-({4-[2-(piperidin-1-yl)ethoxy]phenyl}methyl)naphthalen-2-ol::LY 326315::LY326315

SMILES Oc1ccc(cc1)-c1ccc2cc(O)ccc2c1Cc1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=SSQLMQBZAPRIRS-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19964   

TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19964(6-(4-hydroxyphenyl)-5-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.200nM ΔG°:  -13.1kcal/mole EC50:  1.14nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19964(6-(4-hydroxyphenyl)-5-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.700nM ΔG°:  -12.4kcal/mole EC50:  1.14nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed