BindingDB BDBM21190 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]amino}ethyl)phenol::CHEMBL113142::ZM 241385::ZM241385::[3H]-ZM241385

BDBM21190 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]amino}ethyl)phenol::CHEMBL113142::ZM 241385::ZM241385::[3H]-ZM241385

SMILES Nc1nc(NCCc2ccc(O)cc2)nc2nc(nn12)-c1ccco1

InChI Key InChIKey=PWTBZOIUWZOPFT-UHFFFAOYSA-N

Data 108 KI 16 IC50 4 Kd 2 EC50

PDB links: 29 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 130 hits for monomerid = 21190

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.100nMAssay Description:Binding affinity towards human Adenosine A2a receptor expressed in HEK293 cells using 6 nM [3H]CGS-21680More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.300nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.300nMAssay Description:Binding affinity towards adenosine A2A receptorMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.302nMAssay Description:Antagonist activity at A2AR (unknown origin)More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.302nMAssay Description:Antagonist activity at A2AR (unknown origin)More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.400nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.400nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.800nMAssay Description:Binding affinity to human adenosine A2A receptorMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.800nMAssay Description:Binding affinity against human Adenosine A2a receptor (hA2a)More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.800nMAssay Description:Inhibition of human recombinant adenosine receptor A2aMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.800nMAssay Description:Antagonist activity at human adenosine 2A receptorMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.800nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.870nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.900nMAssay Description:Inhibition of [3H]ZM-241385 binding to adenosine A2a receptor of rat brain tissueMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.900nMAssay Description:Inhibition of [3H]-ZM-241,385 binidng to rat brain adenosine A2a receptorMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.910nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 0.930nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting meth...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.20nMAssay Description:Displacement of [125I]Z241385 from human cloned adenosine A2A receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.20nMAssay Description:Displacement of [3H]NECA from adenosine A2A receptor in Sprague-Dawley rat striatal membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.30nMAssay Description:Displacement of [3H]NECA from Sprague-Dawley rat striatal membrane A2A adenosine receptor by scintillation counting analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.30nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO cell membranes after 1 hr by TopCount microplate scintillation count...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.40nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.40nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in Sprague-Dawley rat striatal membranesMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.40nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.60nMAssay Description:Antagonist activity at adenosine A2A receptor (unknown origin)More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.60nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor by scintillation spectroscopyMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.60nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cell membrane incubated for 1 hr by microplate beta scintillation ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.60nMAssay Description:Antagonist activity at adenosine A2A receptor (unknown origin)More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.60nMAssay Description:Antagonist activity at human adenosine A2A receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.90nMAssay Description:Displacement of [3H]HZ241385 from human A2AAR expressed in HeLa cell membrane incubated for 30 mins by microbeta trilux scintillation counter analysi...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.90nMAssay Description:Displacement of [3H]ZM241385 from human Adenosine A2A receptor expressed in HeLa cells after 30 minsMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
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Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.90nMAssay Description:Displacement of [3H]ZM241385 from human recombinant A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by radioligand binding ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.90nMAssay Description:Displacement of [3H]4-(2-[7-amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol from human adenosine A2A receptor expressed ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.90nMAssay Description:Displacement [3H]ZM241385 from adenosine A2A receptor in human HeLa cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.90nMAssay Description:Displacement of [3H]ZM2421385 from adenosine A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by scintillation counting meth...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 1.90nMAssay Description:Displacement of [3H]ZM241385 from human recombinant A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by radioligand binding ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 2nMAssay Description:Displacement of [3H]ZM241385 from stabilized human adenosine receptor A2a expressed in HEK293 cells followed by receptor capturing on Biocore chips b...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 2nMAssay Description:Displacement of [3H]NECA from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 2nMAssay Description:Antagonist activity at rat A2A adenosine receptorMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 2.20nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 2.60nMAssay Description:Displacement of [3H]SCH58261 from adenosine A2A receptor membrane (unknown origin) measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 2.80nMAssay Description:Displacement of [3H]NECA from rat adenosine A2A receptor expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals

Curated by PDSP K_i Database

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 2.90nMAssay Description:Displacement of [3H]NECA from adenosine A2A receptor in Sprague-Dawley rat striatal membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 5.30nMAssay Description:Displacement of MRS5346 from C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pich...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2b(Homo sapiens (Human))
Universidad De M£Laga

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 19.3nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A2B receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair

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Adenosine receptor A2b(Homo sapiens (Human))
Universidad De M£Laga

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 28nMAssay Description:Displacement of [3H]ZM-241385 from human A2B receptor expressed in HEK-293 cell membranesMore data for this Ligand-Target Pair

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Adenosine receptor A2b(Homo sapiens (Human))
Universidad De M£Laga

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 30nMAssay Description:Selectivity for recombinant human adenosine A2b receptorMore data for this Ligand-Target Pair

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Adenosine receptor A2b(Homo sapiens (Human))
Universidad De M£Laga

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 31nMMore data for this Ligand-Target Pair

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Adenosine receptor A2b(Homo sapiens (Human))
Universidad De M£Laga

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 31nMMore data for this Ligand-Target Pair

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Adenosine receptor A2b(Homo sapiens (Human))
Universidad De M£Laga

Curated by ChEMBL

PNG

BDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)

Ki: 31.6nMMore data for this Ligand-Target Pair

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Displayed 1 to 50 (of 130 total ) | Next | Last >>

Filter my 130 hits

Targets 7▿
- Adenosine receptor A2a 65
- Adenosine receptor A1 28
- Adenosine receptor A2b 20
- Adenosine receptor A3 13
- D(2) dopamine receptor 2
- Histone deacetylase 6 1
- Histone deacetylase 1 1
- ...
Publications 45▿
- J Med Chem 62: 9315-9330 (2019) 8
- Eur J Med Chem 187: (2020) 8
- J Med Chem 59: 10564-10576 (2016) 7
- Eur J Med Chem 155: 552-561 (2018) 6
- Mol Pharmacol 56: 705-13 (1999) 5
- Bioorg Med Chem Lett 30: (2020) 5
- J Med Chem 64: 458-480 (2021) 4
- Naunyn Schmiedebergs Arch Pharmacol 359: 7-10 (1999) 4
- J Med Chem 60: 3372-3382 (2017) 4
- J Med Chem 57: 3623-50 (2014) 4
- J Med Chem 63: 7721-7739 (2020) 4
- Mol Pharmacol 61: 415-24 (2002) 4
- Bioorg Med Chem Lett 23: 3427-33 (2013) 4
- J Med Chem 65: 2091-2106 (2022) 4
- J Med Chem 58: 718-38 (2015) 4
- J Med Chem 59: 1967-83 (2016) 4
- J Med Chem 52: 7640-52 (2009) 3
- J Med Chem 47: 4291-9 (2004) 3
- ACS Med Chem Lett 13: 1172-1181 (2022) 3
- Eur J Med Chem 144: 151-163 (2018) 3
- J Med Chem 63: 12196-12212 (2020) 3
- J Med Chem 64: 16573-16597 (2021) 3
- Br J Pharmacol 115: 1096-102 (1995) 2
- Bioorg Med Chem 23: 6641-9 (2015) 2
- J Med Chem 59: 6470-9 (2016) 2
- J Med Chem 48: 2009-18 (2005) 2
- Eur J Med Chem 44: 2122-7 (2009) 2
- J Med Chem 48: 6887-96 (2005) 2
- Bioorg Med Chem Lett 26: 734-8 (2016) 2
- Eur J Med Chem 227: (2022) 2
- J Med Chem 51: 1730-9 (2008) 2
- Bioorg Med Chem Lett 14: 3307-12 (2004) 2
- J Med Chem 51: 4449-55 (2008) 1
- Bioorg Med Chem Lett 15: 4809-13 (2005) 1
- Bioorg Med Chem 18: 2081-8 (2010) 1
- Eur J Med Chem 241: (2022) 1
- J Med Chem 62: 8511-8531 (2019) 1
- Eur J Med Chem 108: 529-41 (2016) 1
- J Med Chem 54: 4312-23 (2011) 1
- ACS Med Chem Lett 8: 660-665 (2017) 1
- J Med Chem 61: 4301-4316 (2018) 1
- J Med Chem 59: 788-809 (2016) 1
- J Med Chem 51: 1719-29 (2008) 1
- Eur J Med Chem 104: 177-88 (2015) 1
- J Med Chem 39: 398-406 (1996) 1
Institutions 28▿
- Uppsala University 20
- Universit£ 20
- North-West University 10
- Nankai University 8
- Monash University (Parkville Campus) 8
- Universidade De Santiago De Compostela 8
- Biogen Idec 6
- University Of Virginia 5
- Merck Research Laboratories 4
- University Of Ferrara 4
- Schering-Plough Research Institute 4
- Neuroscience 3
- Shanghaitech University 3
- Fudan University 3
- Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer 3
- University Of Dundee 3
- Heptares Therapeutics 3
- Zeneca Pharmaceuticals 2
- Isf College Of Pharmacy 2
- University Institute Of Pharmaceutical Sciences 2
- F. Hoffmann-La Roche 2
- Kissei Pharmaceutical 1
- Univ. Lille 1
- National Institute Of Diabetes 1
- Universidad De M£Laga 1
- Leiden/Amsterdam Center For Drug Research 1
- University Of Bonn 1
- Georgia Institute Of Technology 1
Affinity: 0.10 to 9.9E+8 nM▿
- Ki 108
- IC50 16
- Kd 4
- EC50 2
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 1