BDBM22351 1,3-Diarylprop-2-yn-1-one, 13h::1-(4-fluorophenyl)-3-(4-methanesulfonylphenyl)prop-2-yn-1-one::CHEMBL427356
SMILES CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1ccc(F)cc1
InChI Key InChIKey=MLUHCMRZZNXKAQ-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 22351
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 1More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 2More data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair