BDBM26128 (4-fluorophenyl)boranediol::CHEMBL344890::Phenylboronic Acid, 7

SMILES OB(O)c1ccc(F)cc1

InChI Key InChIKey=LBUNNMJLXWQQBY-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26128   

TargetBeta-lactamase(Escherichia coli)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM26128((4-fluorophenyl)boranediol | CHEMBL344890 | Phenyl...)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibitory activity against E. coli AmpC beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Saccharomyces cerevisiae S288c)
Anacor Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26128((4-fluorophenyl)boranediol | CHEMBL344890 | Phenyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Oxford

LigandPNGBDBM26128((4-fluorophenyl)boranediol | CHEMBL344890 | Phenyl...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM26128((4-fluorophenyl)boranediol | CHEMBL344890 | Phenyl...)
Affinity DataAssay Description:The endpoint enzymatic assay was developed to quantify human recombinant MGL activity with 2-AG. The formation of arachidonic acid and depletion of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed