BDBM264260 6-(2,6-Dichlorophenyl)-8-(3-hydroxyprop-1-yn-1-yl)-2-((3-methyl-4-(piperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 14

SMILES Cc1cc(Nc2ncc3c(=O)n(-c4c(Cl)cccc4Cl)cc(C#CCO)c3n2)ccc1N1CCNCC1

InChI Key InChIKey=LGFRDPWFQMRGBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264260   

TargetWee1-like protein kinase(Human)
Almac Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 264260BDBM264260(6-(2,6-Dichlorophenyl)-8-(3-hydroxyprop-1-yn-1-yl)...)
Affinity DataIC50: 10nMT: 2°CAssay Description:In the measurement of Wee-1 activity, a commercial peptide Poly(Lys Tyr(4:1)) hydrobromide was purchased from Sigma Aldrich and used as the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent