BDBM265638 US9718808, 81

SMILES CN(Cc1ccc2C(=O)OCc2c1C)[C@H]1CC[C@]2(CCN(C2=O)C2=C(C)C(=O)OC2)CC1

InChI Key InChIKey=IPMDRPNJVNITEH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 265638   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 265638BDBM265638(US9718808, 81)
Affinity DataIC50: 690nMAssay Description:A Thallium Flux Assay was performed on each of the final product compounds of the Examples. This assay has been described previously; see, e.g., PCT ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 265638BDBM265638(US9718808, 81)
Affinity DataIC50: 1.18E+3nMAssay Description:A Thallium Flux Assay was performed on each of the final product compounds of the Examples. This assay has been described previously; see, e.g., PCT ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
US Patent