BDBM267057 2-Hydroxyethyl 4-{[(5'-fluoro-2'-hydroxybiphenyl-3-yl)sulfonyl]amino}-2-hydroxybenzoate::US9718809, 183

SMILES OCCOC(=O)c1ccc(NS(=O)(=O)c2cccc(c2)-c2cc(F)ccc2O)cc1O

InChI Key InChIKey=QRDFCYMUXHUTCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267057   

Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM267057(2-Hydroxyethyl 4-{[(5'-fluoro-2'-hydroxybiphenyl-3...)
Affinity DataIC50:  2.60E+3nMAssay Description:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM267057(2-Hydroxyethyl 4-{[(5'-fluoro-2'-hydroxybiphenyl-3...)
Affinity DataIC50:  200nMAssay Description:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...More data for this Ligand-Target Pair
In DepthDetails US Patent