BDBM269327 2-(2-fluoro-4-(6-fluoronaphthalen-2-yl)phenyl)-4,4-dimethyl-1-((1-(1-methylcyclopropanecarbonyl)azetidin-3-yl)methyl)-1H-imidazol-5(4H)-one ::US10413545, Compound 72::US9718813, Compound 72
SMILES CC1(CC1)C(=O)N1CC(CN2C(=O)C(C)(C)N=C2c2ccc(cc2F)-c2ccc3cc(F)ccc3c2)C1
InChI Key InChIKey=UDVYJDDXFMTKLM-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 269327
Affinity DataIC50: 35.5nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Affinity DataIC50: 35.5nMAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Affinity DataIC50: 58.9nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair