BDBM272099 5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(2,2,2- trifluoroethyl)-4,5,6,7-tetrahydro-1H-indazole-5- carboxamide and 5-(3-fluoro-2-methylphenyl)-N- hydroxy-2-(2,2,2-trifluoroethyl)-4,5,6,7-tetrahydro- 2H-indazole-5-carboxamide::US10065948, 35

SMILES Cc1c(F)cccc1C1(CCc2nn(CC(F)(F)F)cc2C1)C(=O)NO

InChI Key InChIKey=NCZJWPBNAKMSSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272099   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 272099BDBM272099(5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(2,2,2- tr...)
Affinity DataIC50: 1.70E+3nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent