BDBM275093 US10221195, Example 40::US9879032, Example 35

SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cnc2OCC3(CC3)NC(=O)c2c1

InChI Key InChIKey=IINYFEFQQZCRDE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 275093   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM275093(US10221195, Example 40 | US9879032, Example 35)
Affinity DataIC50:  1.10nMT: 2°CAssay Description:COS 1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM275093(US10221195, Example 40 | US9879032, Example 35)
Affinity DataIC50:  1.90nMAssay Description:COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM275093(US10221195, Example 40 | US9879032, Example 35)
Affinity DataIC50:  1.10nMAssay Description:COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent