BDBM27652 1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-3-yl)-N-[(3-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::pyrazole scaffold, 7e
SMILES COc1cccc(CNC(=O)c2cc(nn2-c2csc(CNC(=O)[C@H](C)N)c2)C(F)(F)F)c1
InChI Key InChIKey=ZANVLOGENAXDEA-LBPRGKRZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 27652
Affinity DataIC50: 370nMpH: 9.0 T: 2°CAssay Description:Histone H3 is used as the substrate for CARM-1 enzyme, and the methylation is monitored using tritiated S-Adenosyl-Methionine (SAM) as a methyl donor...More data for this Ligand-Target Pair