BDBM276753 N-(1,3-dihydroxy-2- methylpropan-2-yl)-2-(5- ((3-ethoxypyridin-2- yl)oxy)pyridin-3-yl) pyrimidine-5-carboxamide::US10071992, Example 3.2

SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC(C)(CO)CCO

InChI Key InChIKey=ABMPUDBHFWWYQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 276753   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM276753(N-(1,3-dihydroxy-2- methylpropan-2-yl)-2-(5- ((3-e...)
Affinity DataIC50:  83.6nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent