BDBM281806 (S)-5-cyano-N-(1-(4-fluorophenyl) ethyl)-2-(((5-(1-methyl-1H- imidazo[4,5-c]quinolin-8-yl) thiophen-2-yl)methyl)amino) nicotinamide::US10030016, Example 2.28

SMILES C[C@H](NC(=O)c1cc(cnc1NCc1ccc(s1)-c1ccc2ncc3ncn(C)c3c2c1)C#N)c1ccc(F)cc1

InChI Key InChIKey=YYUNHAMGEBGTRX-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281806   

Target3-phosphoinositide-dependent protein kinase 1 [51-359](Homo sapiens (Human))
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM281806((S)-5-cyano-N-(1-(4-fluorophenyl) ethyl)-2-(((5-(1...)
Affinity DataIC50: <100nMAssay Description:PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent