BDBM284873 7-(2-(4-methylpiperazin-1-yl)pyridin- 4-yl)-5-(1-(tetrahydro-2H-pyran-4- yl)-1H-pyrazol-5-yl)pyrrolo[2,1-f] [1,2,4]triazin-4-amine::US10023576, Example 64

SMILES CN1CCN(CC1)c1cc(ccn1)-c1cc(-c2cnnn2C2CCOCC2)c2c(N)ncnn12

InChI Key InChIKey=MABJNNPQZGVNKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284873   

LigandChemical structure of BindingDB Monomer ID 284873BDBM284873(US10023576, Example 64 | 7-(2-(4-methylpiperazin-1...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent