BDBM284883 4-{6-[4-amino-5-(1-methyl-1H- pyrazol-4-yl)pyrrolo[2,1-f][1,2,4] triazin-7-yl]-1H-indazol-1-yl}-1lambda6- thiane-1,1-dione::US10023576, Example 74

SMILES Cn1cc(cn1)-c1cc(-c2ccc3cnn(C4CCS(=O)(=O)CC4)c3c2)n2ncnc(N)c12

InChI Key InChIKey=ZRPRMFVDWQIWGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284883   

LigandChemical structure of BindingDB Monomer ID 284883BDBM284883(US10023576, Example 74 | 4-{6-[4-amino-5-(1-methyl...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
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Date in BDB:
1/11/2019
Entry Details
US Patent