BDBM284921 (4-(4-amino-5-(trifluoromethyl) pyrrolo[2,1-f][1,2,4]triazin-7-yl) morpholin-2-yl)(pyrrolidin-1-yl) methanone::US10023576, Example 113

SMILES Nc1ncnn2c(cc(c12)C(F)(F)F)N1CCOC(C1)C(=O)N1CCCC1

InChI Key InChIKey=KPGMFQMFZRRLII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284921   

LigandChemical structure of BindingDB Monomer ID 284921BDBM284921(US10023576, Example 113 | (4-(4-amino-5-(trifluoro...)
Affinity DataIC50: 111nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent