BDBM285071 3-amino-5-[2-(cyclopropylmethoxy)-5- methylsulfonylphenyl]-1-methylpyridin-2-one::BDBM485915::US10023592, Example 116

SMILES Cn1cc(cc(N)c1=O)-c1cc(ccc1OCC1CC1)S(C)(=O)=O

InChI Key InChIKey=BKMRBHGBWCRLHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285071   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 285071BDBM285071(US10023592, Example 116 | 3-amino-5-[2-(cyclopropy...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 285071BDBM285071(US10023592, Example 116 | 3-amino-5-[2-(cyclopropy...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent