BDBM285544 3-(4-cyano-2-fluoro-5-methylphenyl)-N-cyclopropyl-imidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 17::US10669279, Example 17::US9598421, Example 17

SMILES Cc1cc(-c2c(nc3cccnn23)C(=O)NC2CC2)c(F)cc1C#N

InChI Key InChIKey=SAWDLJNAAJBRMX-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285544   

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 89.9nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 89.9nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 89.9nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 175nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 175nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 175nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 216nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 216nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 216nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 1.82E+4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 1.82E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285544BDBM285544(US10077269, Example 17 | 3-(4-cyano-2-fluoro-5-met...)
Affinity DataIC50: 1.82E+4nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent