BDBM286463 2-(6-Methoxy-4-((3-(2-methoxypyrimidin-5-yl)benzyl)oxy)benzofuran-2-yl)-6-methylimidazo[1,2-b]pyridazine::US9518064, Example 82

SMILES COc1cc(OCc2cccc(c2)-c2cnc(OC)nc2)c2cc(oc2c1)-c1cn2nc(C)ccc2n1

InChI Key InChIKey=XUJYIGYGVFXHSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286463   

TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 286463BDBM286463(2-(6-Methoxy-4-((3-(2-methoxypyrimidin-5-yl)benzyl...)
Affinity DataIC50: 1.32nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent