BDBM293840 3-({[(4R)-7-{methyl[4-(trifluoromethoxy)phenyl]amino}-3,4-::US10106534, Example 182

SMILES CN(c1ccc(OC(F)(F)F)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key InChIKey=PWMKDTPALKGANC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293840   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 293840BDBM293840(US10106534, Example 182 | 3-({[(4R)-7-{methyl[4-(t...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 293840BDBM293840(US10106534, Example 182 | 3-({[(4R)-7-{methyl[4-(t...)
Affinity DataIC50: 5.50E+3nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent