BDBM295252 3-(6-amino-5-(2-methyloxazol-5-yl)pyridin-3-yl)-N-((1S,3S)-3-hydroxycyclohexyl)-4-methylbenzenesulfonamide::US10112926, Example 112

SMILES Cc1ncc(o1)-c1cc(cnc1N)-c1cc(ccc1C)S(=O)(=O)N[C@H]1CCC[C@H](O)C1

InChI Key InChIKey=YVBUTAWXLPEFFD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 295252   

LigandChemical structure of BindingDB Monomer ID 295252BDBM295252(US10112926, Example 112 | 3-(6-amino-5-(2-methylox...)
Affinity DataIC50: 38nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 295252BDBM295252(US10112926, Example 112 | 3-(6-amino-5-(2-methylox...)
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 295252BDBM295252(US10112926, Example 112 | 3-(6-amino-5-(2-methylox...)
Affinity DataIC50: 410nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 295252BDBM295252(US10112926, Example 112 | 3-(6-amino-5-(2-methylox...)
Affinity DataIC50: 660nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

TargetPhosphatidylinositol 4-kinase beta(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 295252BDBM295252(US10112926, Example 112 | 3-(6-amino-5-(2-methylox...)
Affinity DataIC50: 730nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 295252BDBM295252(US10112926, Example 112 | 3-(6-amino-5-(2-methylox...)
Affinity DataIC50: 3.50E+3nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent