BDBM29671 (E)-2-cyano-3-[4-keto-9-methyl-2-(4-piperonylpiperazino)pyrido[1,2-a]pyrimidin-3-yl]acrylamide::(E)-3-[2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-acrylamide::(E)-3-[2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-9-methyl-4-oxo-3-pyrido[1,2-a]pyrimidinyl]-2-cyano-2-propenamide::(E)-3-[2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-9-methyl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-prop-2-enamide::(E)-3-[2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-9-methyl-4-oxopyrido[1,2-a]pyrimidin-3-yl]-2-cyanoprop-2-enamide::MLS000580374::SMR000220632::cid_5922350

SMILES Cc1cccn2c1nc(N1CCN(Cc3ccc4OCOc4c3)CC1)c(\C=C(/C#N)C(N)=O)c2=O

InChI Key InChIKey=UFNOGMROBMXWCI-LDADJPATSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29671   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29671((E)-2-cyano-3-[4-keto-9-methyl-2-(4-piperonylpiper...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29671((E)-2-cyano-3-[4-keto-9-methyl-2-(4-piperonylpiper...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay