BDBM30644 5-ethyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)thiophene-2-sulfonamide::5-ethyl-N-[4-(2-thiazolo[5,4-b]pyridinyl)phenyl]-2-thiophenesulfonamide::5-ethyl-N-[4-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]thiophene-2-sulfonamide::MLS-0111397.0001::cid_9550341

SMILES CCc1ccc(s1)S(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1

InChI Key InChIKey=VQZRFCWLDLNJNL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30644   

TargetImportin subunit alpha-1(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM30644(5-ethyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)thi...)
Affinity DataEC50:  9.71E+3nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM30644(5-ethyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)thi...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay