BDBM30783 2,5-diketo-8-methyl-1-thiazol-2-yl-dipyrido[1,2-e:4',3'-f]pyrimidine-3-carbonitrile::8-methyl-2,5-bis(oxidanylidene)-1-(1,3-thiazol-2-yl)dipyrido[1,2-e:4',3'-f]pyrimidine-3-carbonitrile::8-methyl-2,5-dioxo-1-(1,3-thiazol-2-yl)dipyrido[1,2-e:4',3'-f]pyrimidine-3-carbonitrile::8-methyl-2,5-dioxo-1-(2-thiazolyl)-3-dipyrido[1,2-e:4',3'-f]pyrimidinecarbonitrile::MLS000084423::SMR000047276::cid_665934

SMILES Cc1ccc2nc3n(-c4nccs4)c(=O)c(cc3c(=O)n2c1)C#N

InChI Key InChIKey=GMABSQHMTMQRTP-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 30783   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30783(2,5-diketo-8-methyl-1-thiazol-2-yl-dipyrido[1,2-e:...)
Affinity DataEC50:  1.43E+4nMpH: 7.4 T: 2°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis H37Rv)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM30783(2,5-diketo-8-methyl-1-thiazol-2-yl-dipyrido[1,2-e:...)
Affinity DataIC50:  2.33E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Michael McNeil, Colorado State Universi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30783(2,5-diketo-8-methyl-1-thiazol-2-yl-dipyrido[1,2-e:...)
Affinity DataEC50:  1.06E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30783(2,5-diketo-8-methyl-1-thiazol-2-yl-dipyrido[1,2-e:...)
Affinity DataEC50: >4.50E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Networ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay