BDBM31158 3-hydroxyquinolin-2(1H)-one, 12

SMILES Cc1ccc2cc(O)c(=O)[nH]c2c1

InChI Key InChIKey=BAUHXXRSZJRUOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31158   

TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31158(3-hydroxyquinolin-2(1H)-one, 12)
Affinity DataIC50: 197nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandPNGBDBM31158(3-hydroxyquinolin-2(1H)-one, 12)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM31158(3-hydroxyquinolin-2(1H)-one, 12)
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed