BDBM311836 7-Ethyl-8-(7-methyl-1H-indazol-5-yl)-2-(trifluoromethyl)imidazo[1,2-c]pyrimidine::US10155769, Example 74

SMILES CCc1ncn2cc(nc2c1-c1cc(C)c2[nH]ncc2c1)C(F)(F)F

InChI Key InChIKey=XFBKZSQPDQLSDN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311836   

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311836BDBM311836(US10155769, Example 74 | 7-Ethyl-8-(7-methyl-1H-in...)
Affinity DataIC50: 2nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent