BDBM312593 2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,2-b]pyridazin-6-ol::US9604989, Example 79

SMILES NC1(CCC1)c1ccc(cc1)-c1nc2ccc(O)nn2c1-c1ccccc1

InChI Key InChIKey=KXURUIRWWZYPEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312593   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 312593BDBM312593(US9604989, Example 79 | 2-[4-(1-Aminocyclobutyl)ph...)
Affinity DataIC50: 2.00E+3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 312593BDBM312593(US9604989, Example 79 | 2-[4-(1-Aminocyclobutyl)ph...)
Affinity DataIC50: 2.80E+3nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent