BDBM312820 (4S)-1-[3-[2-[(3R)-3-hydroxy- 1-methyl-2-oxo-pyrrolidin- 3-yl]ethynyl]phenyl]-4- methyl-5,6-dihydro-4H-cyclo- penta[c]pyrazole-3-carbox- amide::US9605005, Example 110

SMILES C[C@H]1CCc2c1c(nn2-c1cccc(c1)C#C[C@]1(O)CCN(C)C1=O)C(N)=O

InChI Key InChIKey=CQCYWIZNPPGUKF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312820   

LigandChemical structure of BindingDB Monomer ID 312820BDBM312820(US9605005, Example 110 | (4S)-1-[3-[2-[(3R)-3-hydr...)
Affinity DataKi:  0.550nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent