BDBM314153 3-{[(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)methyl]amino}pyridine-4-carboxylic acid::US10179769, Example 59::US10807956, Example 59::US11214542, Example 59::US11639333, Example 59::US9611221, Example 59::US9725441, Example 59::US9828343, Example 59

SMILES CC1(C)CCC(CNc2cnccc2C(O)=O)c2ccccc12

InChI Key InChIKey=LRVJADFFCWWTLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 314153   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 314153BDBM314153(US10179769, Example 59 | 3-{[(4,4-dimethyl-1,2,3,4...)
Affinity DataIC50: 550nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 314153BDBM314153(US10179769, Example 59 | 3-{[(4,4-dimethyl-1,2,3,4...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 314153BDBM314153(US10179769, Example 59 | 3-{[(4,4-dimethyl-1,2,3,4...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent