BDBM317598 US9624199, 8::{6-[(2,6-Difluorobenzyl)(methyl)amino]pyridin-3-yl}[(3R)-3-methyl-1,4′-bipiperidin-1′-yl]methanone

SMILES C[C@@H]1CCCN(C1)C1CCN(CC1)C(=O)c1ccc(nc1)N(C)Cc1c(F)cccc1F

InChI Key InChIKey=CQQRHLWMHPZRFU-GOSISDBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317598   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317598(US9624199, 8 | {6-[(2,6-Difluorobenzyl)(methyl)ami...)
Affinity DataIC50:  4.5nMAssay Description:To prepare cell membranes with human α1- and α2-adrenergic receptors, CHO cells stably overexpressing α1- and α2-adrenergic recep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent