BDBM317862 US10807980, Compound 15::US9624217, Compound 15::tert-butyl (S)-3-((4-(ethylsulfonyl)benzyl)carbamoyl)-7-isopropyl-5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3[C@H](C(C)C)N(Cc3c2)C(=O)OC(C)(C)C)cc1

InChI Key InChIKey=VVTMHHKULVDPJF-QFIPXVFZSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317862   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM317862(US10807980, Compound 15 | US9624217, Compound 15 |...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM317862(US10807980, Compound 15 | US9624217, Compound 15 |...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM317862(US10807980, Compound 15 | US9624217, Compound 15 |...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent