BDBM32240 2-[2-(2-fluoranylphenoxy)ethylsulfanyl]pyrimidine-4,6-diamine::2-[2-(2-fluorophenoxy)ethylsulfanyl]pyrimidine-4,6-diamine::2-[2-(2-fluorophenoxy)ethylthio]pyrimidine-4,6-diamine::[6-amino-2-[2-(2-fluorophenoxy)ethylthio]pyrimidin-4-yl]amine::cid_1794610

SMILES Nc1cc(N)nc(SCCOc2ccccc2F)n1

InChI Key InChIKey=XMRJVHFUISUHAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 32240   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 32240BDBM32240(2-[2-(2-fluoranylphenoxy)ethylsulfanyl]pyrimidine-...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay