BDBM32267 6,7-dimethoxy-4-(2-methoxyethylamino)-1H-quinazoline-2-thione::6,7-dimethoxy-4-[(2-methoxyethyl)amino]quinazoline-2(1H)-thione::MLS000045006::SMR000026610::cid_3239316

SMILES COCCNc1[nH]c(=S)nc2cc(OC)c(OC)cc12

InChI Key InChIKey=XMVIBURZSLZRNO-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32267   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32267(6,7-dimethoxy-4-(2-methoxyethylamino)-1H-quinazoli...)
Affinity DataEC50:  7.43E+3nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32267(6,7-dimethoxy-4-(2-methoxyethylamino)-1H-quinazoli...)
Affinity DataEC50:  4.54E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32267(6,7-dimethoxy-4-(2-methoxyethylamino)-1H-quinazoli...)
Affinity DataEC50:  3.86E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay