BDBM322910 2-(1-(4-((4-(4,4-difluoropiperidin-1-yl) phenyl)amino)-5-oxo-5,6- dihydropyrimido[4,5-d]pyridazin-2-yl) piperidin-4-yl)acetonitrile::US10183944, Example 280::US10647720, Ex. # 280
SMILES N#CCC1CCN(c2nc(Nc3ccc(N4CCC(F)(F)CC4)cc3)c3c(=O)[nH]ncc3n2)CC1
InChI Key InChIKey=MEUIVFUNEDFODR-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322910
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair