BDBM32324 6-(2-methoxy-5-methyl-phenyl)benzo[d][2]benzazepine-5,7-dione::6-(2-methoxy-5-methyl-phenyl)benzo[d][2]benzazepine-5,7-quinone::6-(2-methoxy-5-methylphenyl)benzo[d][2]benzazepine-5,7-dione::MLS000682999::SMR000323067::cid_756005

SMILES COc1ccc(C)cc1-n1c(=O)c2ccccc2c2ccccc2c1=O

InChI Key InChIKey=JKZNKRADGAIYOJ-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 32324   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32324(6-(2-methoxy-5-methyl-phenyl)benzo[d][2]benzazepin...)
Affinity DataEC50:  1.87E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 10 [11-204](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32324(6-(2-methoxy-5-methyl-phenyl)benzo[d][2]benzazepin...)
Affinity DataEC50:  1.56E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM32324(6-(2-methoxy-5-methyl-phenyl)benzo[d][2]benzazepin...)
Affinity DataEC50:  1.17E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32324(6-(2-methoxy-5-methyl-phenyl)benzo[d][2]benzazepin...)
Affinity DataEC50:  1.60E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32324(6-(2-methoxy-5-methyl-phenyl)benzo[d][2]benzazepin...)
Affinity DataEC50:  2.42E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay