BDBM324668 1'-({5-Chloro-1-[3- (cyclopropylsulfonyl)propyl]-1H- pyrrolo[3,2-b]pyridin-2- yl}methyl)spiro[cyclopropane-1,3'- pyrrolo[2,3-c]pyridin]-2'(1'H)-one::US10189838, Example 4-6

SMILES Clc1ccc2n(CCCS(=O)(=O)C3CC3)c(CN3C(=O)C4(CC4)c4ccncc34)cc2n1

InChI Key InChIKey=GETTWMCRORBZGP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324668   

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324668BDBM324668(1'-({5-Chloro-1-[3- (cyclopropylsulfonyl)propyl]-1...)
Affinity DataEC50:  29nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent