BDBM329303 4-(5-chloro-6-((1S)-2,2,2- trifluoro-1-methyl-1- phenylethoxy)-3-pyridinyl)-2,5- difluoro-N- (methylsulfonyl)benzamide::4-(5-chloro-6-((1S)-2,2,2-trifluoro-1-methyl-1-phenylethoxy)-3-pyridinyl)-2,5-difluoro-N-(methylsulfonyl)benzamide::US9663508, Example 804

SMILES C[C@](Oc1ncc(cc1Cl)-c1cc(F)c(cc1F)C(=O)NS(C)(=O)=O)(c1ccccc1)C(F)(F)F

InChI Key InChIKey=CQJXWPQFIMNZLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329303   

LigandChemical structure of BindingDB Monomer ID 329303BDBM329303(US9663508, Example 804 | 4-(5-chloro-6-((1S)-2,2,2...)
Affinity DataIC50: 76.9nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 329303BDBM329303(US9663508, Example 804 | 4-(5-chloro-6-((1S)-2,2,2...)
Affinity DataIC50: 3.00E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent