BDBM330140 1-(5H-chromeno[3,4- c]pyridin- 8-yl)-3-(4- methoxyphenethyl) urea::US9663529, Example II-6

SMILES COc1ccc(CCNC(=O)Nc2ccc-3c(OCc4cnccc-34)c2)cc1

InChI Key InChIKey=WNMJUYWTRVMPEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330140   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 330140BDBM330140(US9663529, Example II-6 | 1-(5H-chromeno[3,4- c]py...)
Affinity DataIC50: 1.61E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent