BDBM33214 pyrazolopyridine, 13

SMILES NCC1CN(CCO1)c1c(cnc2[nH]ncc12)-c1ccsc1

InChI Key InChIKey=UMBDBYNAFQJLCQ-UHFFFAOYSA-N

Data  2 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 33214   

TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

LigandPNGBDBM33214(pyrazolopyridine, 13)
Affinity DataIC50:  290nMpH: 7.5 T: 23°CAssay Description:CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

LigandPNGBDBM33214(pyrazolopyridine, 13)
Affinity DatapH: 7.5 T: 23°CAssay Description:CDK1 kinase activity was measured in a DELFIA based HTScan CDK1/CycB kinase assay kit (Cell Signalling Technology) that monitors biotinylated substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

LigandPNGBDBM33214(pyrazolopyridine, 13)
Affinity DataIC50:  4.60E+3nMpH: 7.4 T: 23°CAssay Description:CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed