BDBM341674 2-(4-chloro-2-methylphenoxy)-1-(5-(1-phenyl-1H-pyrazol-4-yl)-7,8-dihydrothiazolo[2',3':2,3]imidazo[4,5-c]pyridin-6(5H)-yl)ethanone::US9765092, Example 6.13.7

SMILES Cc1cc(Cl)ccc1OCC(=O)N1CCc2nc3sccn3c2C1c1cnn(c1)-c1ccccc1

InChI Key InChIKey=DJKRXNILSLMILZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341674   

TargetTryptophan 5-hydroxylase 1(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 341674BDBM341674(US9765092, Example 6.13.7 | 2-(4-chloro-2-methylph...)
Affinity DataIC50: 26nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair
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Date in BDB:
7/29/2019
Entry Details
US Patent