BDBM343322 1-methyl-4-(4-methylpyridin-2-yl)-N-(2-(pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1H-pyrazole-5-carboxamide::US9777000, Example 4.3::US9777000, Example 4.30

SMILES Cc1ccnc(c1)-c1cnn(C)c1C(=O)Nc1ccn2nc(nc2c1)N1CCCC1

InChI Key InChIKey=KSLFNXQNAHOLQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343322   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Mochida Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 343322BDBM343322(US9777000, Example 4.30 | 1-methyl-4-(4-methylpyri...)
Affinity DataIC50: 5nMAssay Description:IMAP TR-FRET Phosphodiersterase Evaluation Assay Kit (Molecular Device) was used for the measurement. Ten μL of a diluted test compound having e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Mochida Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 343322BDBM343322(US9777000, Example 4.30 | 1-methyl-4-(4-methylpyri...)
Affinity DataIC50: 5nMAssay Description:IMAP TR-FRET Phosphodiersterase Evaluation Assay Kit (Molecular Device) was used for the measurement. Ten μL of a diluted test compound having e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent