BDBM345248 (1r,4r)-1-(3-fluoro-2-methylphenyl)-N-hydroxy-4-phenoxycyclohexanecarboxamide::US9783488, Example 101

SMILES Cc1c(F)cccc1[C@]1(C(=O)NO)CC[C@H](Oc2ccccc2)CC1

InChI Key InChIKey=ADVKDBSKBQIPTJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345248   

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345248BDBM345248((1r,4r)-1-(3-fluoro-2-methylphenyl)-N-hydroxy-4-ph...)
Affinity DataIC50: 680nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent